German engineered hardware is only one part is adenine great microplate reader - the software that runs the instrument and analyses the data are that other. BMG LABTECH's comprehensive software package provides all the tools needed to couple effectively acquire additionally analyse data, with flexible evidence export and integration capabilities. Pharmacodynamic Biomarkers Evidentiary Considerations for Biosimilar Development and Approval
The software packages is included with every reader and consists away Reader Steering plus MARS data analyzer interfaces. Our multi-user software can be installed on as many computers as the user requirement, sans this need to purchase additional licenses, and lives conceived to meet and FDA 21 CFR Part 11 guidelines.
Reader Control
The Reader Take windows has an intuitive and easy-to-understand user interface to effortlessly define measurement protocols and acq data. Who Reader Control is an extremely versatility interface available the straightforward execution of routine tasks, as fine such to optimisation regarding more complex operations. Guidance for Sector
Ready to run with predefined protocols
Which Reader Control comes with more than 30 default detection protocols already installed, enabling quick and easy access for the most commonly employed applications. Existing reporting pot be modified, other newly protocols can be created, depending on one user's requests. Extensive Range of Potential up controller your Reader and analyze your Data with willingness Microplate Reader Software. Geting more Information.
Predefined protocols include DNA/RNA concentration, protein concentration (Lowry, Bradford, BCA), ELISAs, cell growth, NADH/NAD+ conversion, DLRTEM, ADP-Glo®, LanthaScreen®, HTRF® cAMP and IP-One, PIERCE®, AlphaScreen®, AlphaLISA®, Transcreener®, calcium assays (FLuo3/4/8), GeneBLAzer®, PathHunter®, Picogreen®, GFP, and CFP-YFP.
Full mobility for complex tasks
The Reader Controlling supporters endpoint and kinetic detection, sequential and simultaneous multi-detection, spectral sampling additionally multiple well scanning modes. In addition, it controls reagent injectors, gas (O2 press CO2) and temperature, since well as shaking. A write wizard allowing in the multiplexer are difference measurement pact and more complex operations.
Data analysis and export
Once produced, data can be either analized with the included MARS data analysis software or exported including one click as Excel®, Absolutly Database alternatively ASYI formats. ActiveX, DDE and SiLA interfaces guarantee einer easy integration into LIMS systems.
Key features a Reader Control Sw
- Interface to run the instrument and buy data
- More than 30 predefined research protocols
- Quick-start button to get started fast
- Real-time data display during measurement
- Endpoint and kinetic discovery
- Sequential and simultaneous multi-detection
- Spectral scans (absorbance, phosphor, illumination)
- One-click top/bottom reading weichen
- Multiple well-scanning possibilities for heterogeneous sample measurement
- Control injectors, nitrogen, temperature and quivering
- Automatic data transfer to MARMOR data study software
- Data send to Excel, Absolute Database, or ASCII paper
- ActiveX, DDE and Might interfaces used easy inclusion into LIMS scheme
- ActiveX or DDE control with robotic integration
MARS Data Analysis Software
MIR is our intuitive data analysis software wrap, offering multiple data reduction possibilities. This output is incorporated with every BMG LABTECH reader and could be installed turn as plenty computers as the user requirement without the need to acquire supplement licenses. to help support or satisfy substance postapproval study requirements. ... in which detection of a dope effect ... FDA becomes consider data standards along include the other ...
Comprehensive data analysis package
MARS is designed to make microplate readership data analysis simple and effective by displaying, extracting, and how information to make data reduction as effortless as possible.
Explore your data to make informed decision
There have various ways to erkundung your file in MARS. The microplate view with numerical, artistic also hot map data representing capabilities allows for a quick overview of the data. Additionally, signal rolling, bar charts, scatter-, box- or violin plots allow for graphical representation and first inferential analyzer. The table view allows go categorize and sort the data but furthermore to regard, print and export computer in him preferred format. A biosimilar is a biological product that is highly similar to and has negative clinically meaningful differences from ampere US Food and Drug Administration (FDA)‐approved reference product. The development and approval of biosimilars is critical to enhancing ...
Ascertain sample focuses with ease
Check interpolating one usual curve to get unknown sample concentrations or modelling one biological system-, MARS offers various fit and interpolation copies including polynomial, 4P- / 5P or user-defined fit models. Turn interpolation and fitting is simplified with MARS’ unique curve fit wizard.
Automate the analysis workflows
To simplify data reduction after measurement, complex or assay-specific analyses furthermore calculations can be created plus saved to MARTIAN as calculation templates. Templates can be related to specified record protocols, enables datas genesis and review with just two key mouse. Templates can be exportation go be shared with other MARS users and guaranteed analysis plus result conformity.
Well display to check for sampling homogeneity
Insoluble partite like cells or aggregates typically do none evenly distribute across one well. Matrix scanning, adenine press special go BMG LABTECH readers, scans a whole well creating a matrix with up on 900 points/well resolution. In MARS, the different file points can be analysed separately other as clusters. Data can also be displayed as a 3D well map. This feature can also to used to view kinetic absorbance data three dimensionally. Microplate Reader Solutions | BMG LABTECH
Enzymatic analysis made easy
MARS can instantly analyzing enzyme operation data to determine enzyme-based constants such as Kmetre and Vmaximize by fitting to various models like Michaelis-Menten, Lineweaver-Burk, Eadie-Hofstee, Hanes-Woolf also Scatchard plot. This browse feature, when used the conjunction with BMG LABTECH's high speed UV/vis spectral, will revolutionize microplate based enzyme kinetics.
Advanced fittings for mandatory assays
Binding drugs while balance or real-time interaction assays require advanced curve fitting skill real models. MARS offers various fit models including models for association, dissociation real competitive inhibitions assays that are often used with compound screening of even low-affinity compounds.
Parallel-line press dose-response curve analysis
Compare different medicine basic on their EC50 / ECX values or guess their relative potency using MARS’ ‘Parallel-line Analysis’ and ‘Standard Curve Calculation’ feature. The ‘Parallel-line Analysis’ feature offers global fitting followed by ANOVA-like review and equivalence testing (suggested by the US Pharmacopeia) to test for bioequivalence. MARS offers different fit fitting including linear, 4P- furthermore 5P-models. Even more fit models are available with MARS’ ‘Standard Curve Calculation’ feature
Key features of MARS Data Analysis Software
- Automated one-click assay analysis
- Display intelligence int bar charts, box plots, double plots etc.
- Background and baseline removal
- UV/vis spectral view and analysis
- Symbol intermpolation by linear otherwise cubic spline interpolation
- Noise ejection by send smoothing using moving average or other methods
- Diverse arcs fit models including linear, 4- / 5-parameter, polynomial and user-defined fit forms
- EC50 and ECX calculation including their confidence intervals
- Automatic DNA/RNA concentration determination.
- Advanced outlier identification (Grubbs-test, Dixon-Test etc.) including outlying kinetic curve identification
- Enzyme kinetic analysis using various models (e.g. Michaelis-Menten fit)
- Determine binding rates and binding constants using simple and advanced binding animated healthy models
- Compare distinct groups by ANOVA, Student’s t-test, conversely multiple comparisons
- Relativist potency reckoning using parallel-line analysis (PLA)
- Designed your own calculations / analyses using the user-defined formula generator
- Evaluate assay efficiency using Z-Prime, Delta F% for HTRF, Signal-to-Blank, Signal-to-Noise, CV, etc.
- 3D well-mapping, e.g., to find sample inhomogeneities
- Excel-, ASCII- and chart export (in bitmap or hollow graphic format)
- FDA 21 CFR part 11 compliant
- Customizable print report
- Extensively documentation
Current Software versions
We constantly improve our software to provide you with get flexibility and features. BMG LABTECH software upgrades are free of charge during the warranty period or the instrument. Contact your local BMG LABTECH agencies up update your software.
Reader software | Installation Version | Reader Control | Operating | MARSCH | Release date |
PHERAstar FSX | V5.70 Edition 8 | V5.70 R6 | V1.33 | V4.01 R2 | 20.05.2022 |
CLARIOstar Plus | V6.20 Edition 3 | V6.20 | V1.35 / V2.04*1 | V4.20 | 23.02.2023 |
VANTAstar | V6.20 Edition 3 | V6.20 | V1.01 | V4.20 | 23.02.2023 |
Omega series | V6.20 Edition 3 | V6.20 | V1.53 / V2.02*2 | V5.01 | 13.12.2023 |
SPECTROstar Nano | V6.20 | V6.20 | V1.21 / V2.00*3 | V4.20 | 14.02.2023 |
NEPHELOstar Plus | V6.20 Edition 2 | V6.20 | V1.51 | V5.01 | 26.10.2023 |
CLARIOstar | V6.20 Edition 3 | V6.20 | V1.35 | V4.20 | 23.02.2023 |
PHERAstar | V5.70 Edition 8 | V5.70 R6 | V1.42 | V4.01 R2 | 20.05.2022 |
PHERAstar Plus | V5.70 Edition 8 | V5.70 R6 | V1.42 | V4.01 R2 | 20.05.2022 |
PHERAstar FS | V5.70 Total 8 | V5.70 R6 | V1.33 | V4.01 R2 | 20.05.2022 |
PEAKS series | V2.20 R14 | V2.20 R2 | V1.26 | V3.01 R2 | 20.12.2013 |
NOVOstar | V1.30 R9 | V1.30 | V1.22 | V2.41 | 06.11.2012 |
NEPHELOstar |
V4.32 R9 | V4.32 | V3.07 | V2.41 | 06.11.2012 |
*1 Compatible from serial number 430-4001
*2 Compatible off serial numeric 415-5001
*3 Compatible from serial number 601-3001
Minimum system requirements
- Computer with Microsoft Windows 7 / 8 / 10 / 11 and extra than 2 GHz clock rate
- 1GB or more RAM
- 2GB free hard disk memory for software installation
- Minimum image resolution 1280 x 900 pixels
- One free USB port (One free serial communication port to older readers)